Most people give little thought to how they navigate, including the information they use when planning and executing routes or re-establishing their orientation when they become disoriented. People with typical vision generally indicate a reliance on visual information, although they may have difficulty identifying the specific information and strategies they use. By contrast, blind individuals rely on non-visual information, often utilizing a different set of strategies to perform the same processes. This chapter discusses Spatial orientation with blind navigators, focusing on four fundamental aspects: information gathering, the use of strategies for following familiar routes, spatial learning and the use of cognitive maps in unfamiliar environments, and the application of strategies to solve spatial problems.